Thanks for your thoughts, I think the reason the oncologist is asking me to stop taking Letrozole is to see if it is causing this painfully condition and until it's out of my system he does not know whether to change to another Al. Talk to your specialist, pharmacist or GP about any complementary therapies, herbal remedies or supplements you want to use before you start using them. Less pain in the knees but still getting better gradually. Breast Cancer Now is a company limited by guarantee registered in England (9347608) and a charity registered in England and Wales (1160558), Scotland (SC045584) and Isle of Man (1200). I hope this helps. Withdrawal: Consult your gynecologist for a better way to discontinue your hormones. #1 is a problem with my hands, unable to make fists or grip a knife to cut meat, hands feeling swollen every morning. Eating healthy meals and becoming more physically active can help you maintain a healthy weight. However, some side effects, such as high cholesterol, lymphedema, osteoporosis, and vaginal dryness may persist despite discontinuation of Arimidex. Always let your dentist know that you are taking letrozole. The amount of Letrozole that you will receive depends on many factors, including your general health or other health problems, and the type of cancer or condition being treated. It is important to strike the correct balance between getting enough rest and staying physically active. This usually improves as your body adjusts to letrozole. You may gain weight when taking hormone therapy. You may also hear it called Femara, which is its best-known brand name. If you’re having chemotherapy or radiotherapy, your specialist will tell you when it’s best to start letrozole. If you have any questions about this, talk to your doctor. Do not take other drugs containing oestrogen, such as hormone replacement therapy (HRT), while you’re taking letrozole as this may interfere with its effectiveness. If your eating problems do not improve, talk to your doctor or nurse. Tell your doctor or nurse if you have ever had problems with blood pressure. Some breast cancers are stimulated to grow by the hormone oestrogen. If you're taking adjuvant hormonal therapy medicine now, stick with it as prescribed. It can help to lower your intake of nicotine, alcohol, and hot beverages containing caffeine such as tea and coffee. If you have to go to the hospital for whatever reason other than cancer, always tell the doctors and nurses that you are taking letrozole. When letrozole is given Many types of breast cancer depend on the hormone estrogen to grow. If you do not have much of an appetite, try eating small meals on a regular schedule and often. Physical activity and maintaining a healthy weight can help reduce joint pain and keep joints flexible. ohilly. Letrozole is usually given after surgery to reduce the risk of breast cancer coming back or spreading. It is also used to treat early breast cancer in women who have experienced menopause and who have already been treated with a medication called tamoxifen (Nolvadex) for 5 years. There are a number of other brands of letrozole, all of which contain the same dose of the drug. They may also recommend that you take calcium and vitamin D supplements. Always inform your doctor or nurse of the side effects you experience. They should be stored away from heat and direct sunlight. It’s best to take it at the same time every day. Do not use if you are pregnant. These drugs are often prescribed after breast cancer surgery, chemotherapy or radiation therapy to help prevent a recurrence of the disease. Letrozole works by reducing the amount of oestrogen made in the body. However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back. Some women find that their appetite increases. Where to Purchase Femara (Letrozole)? There is hope after this med! Non-hormonal creams and gels or lubricants can help reduce vaginal dryness and discomfort during sex. Letrozole is a product that generally do not need to be stopped taking it gradually. Now 2 months later, without letrozole I am feeling much better. 2. You can buy these from a chemist, or your doctor can prescribe them. Instead it's made in the fatty tissues of the body. I have another appt booked at the oncology clinic in early December so I will talk further about it with whomever I see at that time. Although not all of these side effects may occur, if they do occur they may need medical attention. Hormones are substances produced naturally in the body. I finished taking 5 years of first Tamoxifen then Letrozole, 2.5 years each. To hear from us, enter your email address below. If you’re thinking about stopping taking letrozole for any reason, talk to your specialist first. Research has shown that about 25% of women who are prescribed hormonal therapy to reduce the risk of recurrence after surgery either don’t start taking the medicine or stop taking it early, in many cases because of side effects. Your nurse can give you further advice on this. It can help to lower your intake of nicotine, alcohol, and hot beverages containing caffeine such as tea and coffee. Taking regular walks, eating a healthy diet, not smoking, and following guidelines for drinking alcohol will also help strengthen your bones. If this happens, your doctor may give you medicine to lower the cholesterol and fat in the blood. It can cause mild withdrawal symptoms that can include the following:-Dizziness-Nausea-Headache-Sweating-Depression-Insomnia. If you feel drowsy, don't drive or operate heavy machinery. If you forget to take a pill, take one as soon as you remember. Try to pace yourself until this improves. This is there any withdrawal after stop taking letrozole page on EmpowHER Women's Health works best with javascript enabled in your browser. Let your doctor or nurse know if this happens. The level of drug in your body will remain high enough from the day before. 6. If you are taking other drugs, you may have certain side effects that are not listed here. You won’t need to stop taking it gradually. 3. Who it’s suitable for I just read this question and the feedback because I just decided yesterday to stop taking the Letrozole that I've been taking for 7 months. Do not start, stop, or change the dose of any drug without checking with your doctor. You may have pain or stiffness in the joints, or sometimes in your muscles. Taking letrozole with other drugs. Occasionally, letrozole may be used as the first treatment for breast cancer, for example when surgery isn’t appropriate or needs to be delayed. Here, we explain the most common side effects of letrozole. 1. His feeling was that as there is no evidence that continuing Letrozole after 5 years is beneficial, I should stop taking it after December. Some people start taking letrozole after a few years of taking the hormone therapy drug tamoxifen. I hope this … Letrozole is used after surgery and other treatments to reduce the risk of breast cancer returning. Side effects of letrozole Stopping Letrozole? How does letrozole work? 5. Nausea is usually mild, but tell your doctor or nurse if this happens. Your hair will thicken after the treatment ends. Dress in layers so you can remove clothing if you need to. How long will I have to take it? Tell your doctor if your hot flashes become bothersome. It blocks this process and reduces the amount of estrogen in the body. The study also looked at how stopping hormonal therapy affected the women's risk of dying. Before taking this medicine. Some people worry about stopping their treatment, but there’s evidence that exemestane continues to reduce the risk of breast cancer coming back for many years after you stop taking it. Let your doctor know if you have pain or discomfort when urinating, if you urinate more frequently than normal, or if your urine is cloudy or foul-smelling. What happens when you stop taking Letrozole? I stopped taking it a month ago cause My hips and shoulders felt like they were coming out my sockets. Casper says that about 1 percent of people who take letrozole get leg cramps and headaches, but the good news is that these symptoms go away once you stop taking the pills. Arimidex (anastrozole) is a brand-name prescription drug that’s used for certain types of breast cancer. If you have any worries or questions about taking or stopping letrozole, you can call us free on 0808 800 6000 to talk through your concerns. Let your health professionals know if you have any of these symptoms. Except when it is almost time for your next dose, do not take a double dose. If bleeding continues for more than a few days, tell your doctor or nurse. This may increase the risk of bone fractures. Posted: December 2, 2011; If you would like to reproduce some or all of this content, see Reuse of NCI Information for guidance about copyright and permissions. Use effective birth control if you are not past menopause. It should go away when the drug is out of your system which shouldn't take longer than 4 days to a week. Letrozole is also used to control breast cancer that has spread to other parts of the body (secondary breast cancer). Sometimes it may be possible to change to another hormone drug. If hot flashes are troublesome: • Try taking your letrozole at bedtime. Or they may have difficulty concentrating or may feel anxious or have trouble sleeping. Letrozole is suitable for women who have been through the menopause and whose breast cancer is oestrogen receptor positive. If your cancer is hormone receptor negative, then letrozole will not be of any benefit. Always tell your doctor or nurse about any change to your eyesight. Your ankles and feel may swell up because of the build-up of fluid. You may have bleeding when you start this treatment, or if you change to it from another treatment. Do not stop taking letrozole unless your doctor instructs you to. Some people worry about stopping their treatment, but there’s evidence that letrozole continues to reduce the risk of breast cancer coming back for many years after you stop taking it. 4. Get a new prescription before the one you have runs out, and keep track of holidays, when pharmacies may be closed. This is normally mild. You won’t need to stop taking it gradually. This type of breast is called estrogen receptor-positive (ER-positive) breast cancer. If this is the case, make sure you talk to your cancer doctor or nurse. Let your doctor or nurse know if this happens. I had bad joint pain in my knees for the full time and hot flashes as well as some foggy mental functioning. If you’re taking letrozole to treat breast cancer that has come back or spread to another part of the body, you’ll usually take it for as long as it’s keeping the cancer under control. Hormone therapies interfere with the way hormones are made or formed in the body. just been taken off letrozole after one year and four years on tamoxifin It looks like you have javascript turned off. You should take the right dose, not more or less. They can give you drugs to help. What is letrozole? If you’re thinking about stopping taking letrozole for any reason, talk to your specialist first. Dr. Edward Smith answered. Your nurse will monitor it regularly during treatment. If you have any problems with the way your liver works, or any problems with the way your kidneys work. If you miss a dose, you don’t need to take an extra dose the next day. Check with your doctor immediately if any of the following side effects occur while taking letrozole: Less common. They can normally suggest ways to improve the side effects. Doctors sometimes prescribe it before or after another type of hormone therapy. Talk to your specialist or advice line before you stop taking a cancer drug. They can prescribe painkillers and give you advice. Tell your doctor if you notice this or any other type of swelling. If your vaginal bleeding continues for more than a few days, tell your doctor or nurse. This treatment can cause vaginal changes. I completed the full five years as prescribed. Letrozole is used treat early breast cancer in women who have experienced menopause (change of life; end of monthly menstrual periods) and who have had other treatments, such as radiation or surgery to remove the tumor. This medicine may make you dizzy, drowsy, or tired than they are normally. Keep using birth control for at least 3 weeks after your last dose of letrozole. What are some things I need to know or do while I take Letrozole? We have … It is very important that you do not stop taking letrozole without telling your doctor, as this may affect the success of the treatment. #2 is possibly just the inability to bounce … Sometimes letrozole is given alongside a drug called goserelin (Zoladex) to women who haven’t yet been through the menopause. If you are at risk of developing osteoporosis, your doctor may prescribe drugs called bisphosphonate to protect your bones. Explain that you are taking hormone therapy and that no one should start or stop it without taking to your cancer specialist in the first place. Letrozole belongs to a group of drugs called aromatase inhibitors. Posts: 446 Joined: Jan 2008 Apr 10, 2009 - 5:23 pm. If you’re taking any other prescribed or over-the-counter medicines, check with your treatment team or pharmacist if you can take these with letrozole. Why Buy Letrozole? Drink lots of fluids if you think you may have an infection. If this happens, it is likely to occur in the first weeks of treatment or when changing from another hormone therapy to letrozole. Tell your doctor if you are taking any other medication. Always take the pills exactly as your nurse or pharmacist has told you. This includes your doctors, nurses, pharmacists, and dentists. This happens when an enzyme called aromatase changes other hormones into estrogen. It is used to treat breast cancer in women who have gone through menopause. These include complementary therapies and herbal remedies. Some women notice that their hair thins out while they are taking letrozole. Low doses of certain antidepressants can help reduce hot flashes. Your doctor will determine your dose and how long you will be taking Letrozole. It is very important that you contact your doctor immediately if you develop a sever rash. This medicine may increase the amount of cholesterol and fat in the blood. Tell your doctor or nurse if this is a problem. Your treatment team will tell you when to stop taking letrozole. How long after being disease-free from breast cancer is it safe to stop letrozole (Femara)? Less common but more severe side effects of aromatase inhibitors are heart problems, osteoporosis, and broken bones. I had an estrogen cancer and I have been on letrozole for a year. Keep the pills in their original packaging at room temperature. If you accidentally take too much letrozole (Femara), contact a doctor or hospital straight away.You might need medical treatment. Letrozole may cause dizziness. If letrozole stops working, your specialist may prescribe another hormone drug. Taking letrozole for a number of years increases the risk of bone thinning (osteoporosis). After menopause, estrogen is no longer made in the ovaries. Sometimes, doctors give letrozole before surgery to try to reduce the size of the cancer and avoid having to perform a mastectomy (removal of the breast). You may experience some of the side effects mentioned here, though it is rare for a patient to have all of them. It’s sometimes given before surgery to shrink a larger breast cancer. No one responded to my post about this, so I'll try again: I've only been taking Femara, but I'm already wondering: so what happens in 5 or 10 years (new research shows we might have to be on this stuff longer) when we stop taking our aromatase inhibitors? You may develop a mild skin rash. when you first start taking letrozole. For these reasons, before you start taking letrozole it is important that your doctor knows: If you have not yet gone through the menopause, or if there is a possibility you could be pregnant. Bone fracture; breast pain; chest pain Letrozole is taken once a day in tablet form. letrozole is for use only in women who can no longer get pregnant. In rare cases, women may have vaginal bleeding. Even though their ovaries have stopped producing estrogen, it is still produced by the aromatase enzyme found in other tissues. Some people worry about stopping their treatment, but there’s evidence that letrozole continues to reduce the risk of breast cancer coming back for many years after you stop taking it. It can also be given to treat breast cancer that has spread to another part of the body (secondary breast cancer), when it’s often given alongside another drug. Hormone therapy is a very common treatment for secondary breast cancer and many people take it for a long time. Do not stop: Letrozole ... Hi, i stopped taking femara (letrozole) two weeks ago - cold turkey and have been having a lot of headaches, dizziness, nausea, muscle and joint pains, tiredness? If you notice any changes in your heart rate, tell your doctor immediately. I have had several minor side effects, but 2 side effects that I deem as too important to continue taking the daily pill. How it’s taken  These are common and tend to be mild, though they can vary. Return the remaining pills to the hospital if the treatment is discontinued. Sometimes, women have irritated eyes or blurred vision when taking letrozole. Given that one in three patients taking tamoxifen or aromatase inhibitors eventually develop resistance, the researchers … Hot flashes and sweating can subside after the first few months. Most side effects settle down a few months after taking letrozole or can be controlled or managed. Learn about side effects, warnings, dosage, and more. In the study, 13% of women stopped taking the drugs due to side effects such as joint and muscle pain. Letrozole can interact with other drugs. You can use non-hormonal creams, gels or lubricants to help with vaginal dryness and any discomfort during sex. 8. Find out more about the side effects of letrozole. Some women may discover that they feel down when taking letrozole. Along with its needed effects, letrozole may cause some unwanted effects. Tell all of your health care providers that you take letrozole. Talk to your doctor if side effects from Arimidex are persisting despite stopping it. Keep them safe and out of the reach of children. Taking short walks regularly will help you feel less tired. This is important to ensure that it is working as well as possible. If you have a loss of bone density, or 'brittle bones' - a condition known as osteoporosis. When you start to take letrozole, you may feel tired, drowsy, or feel like you have no energy. These are known as oestrogen receptor positive or ER+ breast cancers. There are certain important things to remember when taking the tablets. Your doctor may check your cholesterol levels with a blood test. However, women who are prescribed this product for breast cancer shouldn’t stop taking it unless their doctors recommends to do so. The pills are taken at the same time each day, either in the morning or at night. HOT FLASHES AND SWEATING. Aromatase inhibitors may cause muscle and joint aches and pains. • Some people find it helpful by avoiding alcohol, spicy food, caffeine intake (coffee, tea, colas, chocolate). However, not taking the drug for the recommended time may increase the risk of your breast cancer coming back. One more time/what happens when you stop AIs. Letrozole is a hormone therapy drug. You should not stop taking Letrozole without discussing with your physician. Letrozole is also used in women who have experienced menopause as a first treatment of breast … We’d love to keep in touch about news, events and how you can get involved. Letrozole is a drug used to treat breast cancer in women who have gone through the menopause. "If the side effects from letrozole are intolerable, benefits are maintained by switching to tamoxifen rather that stopping hormonal therapy altogether." You should not use letrozole if you are allergic to it. 54 years experience Neurosurgery. Men with breast cancer may be given letrozole, although another drug called tamoxifen is more commonly used. I know it's scary but I had an allergic reaction to letrozole and had to stop taking all my medication including my in gales and lanzaporole and then slowly introduced them back but not the letrozole I have now been put on exemestane and yes still have joint pain but if it's to bad I take paracetamol. Hot flashes and sweating can subside after the first few months. These are common and tend to be mild, though they can vary. Do not stop taking letrozole unless your doctor instructs you to. This includes medications that can be purchased in a store or pharmacy. Letrozole is a drug called an aromatase inhibitor. This is why, this product can be stopped abruptly. Letrozole can also be used to treat breast cancer that has come back (recurrence). Unlike the drug clomiphene, which was prescribed in the past, letrozole doesn’t cause mood changes or affect the endometrial lining or cervical mucus. To improve the side effects settle down a few days, tell your doctor nurse. 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